Offers anticholinergic effect to counter imbalance caused by antidopaminergic drugs.
Also counters abnormal movement in ageing.
Helpful in acute life-threatening episodes (ALTEs) caused during Rett syndrome (RS).
"Trihexyphenidyl with significantly reduced frequency of the ALTEs. "Trihexyphenidyl in RS patients with similar presentations can modify .the dystonia and prevent ALTEs.
[Gika AD, Hughes E, Goyal S, Sparkes M, Lin JP.Mov Disord. 2010 Feb 15;25(3):385-9].
Indicated In :
- Parkinsonism (postencephalitic, arteriosclerotic and idiopathic)
- Rubral tremor and dystonias
- Palatal myoclonus and acquired pendular nystagmus
- clozapine-induced nocturnal hypersalivation
- As adjunct with antipsychotic therapy to control EPS
Dosage and administration :
( A ) As initial therapy for parkinsonism : One half Tablet to 6-10 mg daily
( B ) Drug-induced Parkinsonism : 1mg-15 mg as per requirement
( C ) Concomitant use with Levodopa : 3-6 mg daily in divided doses
Price: