PRUCALOPRIDE SUCCINATE 2 MG

PRUCALOPRIDE SUCCINATE 2 MG Specification

Origin of Medicine
India

Pacakaging (Quantity Per Box)
10X10 Tablet

Drug Type
General Medicines

Physical Form
Tablets

Dosage Guidelines
As directed by the physician

Storage Instructions
Keep it in cool or dry place

PRUCALOPRIDE SUCCINATE 2 MG Trade Information

Minimum Order Quantity
10 Pieces

Supply Ability
5000 Pieces Per Month

Delivery Time
1 Week

About PRUCALOPRIDE SUCCINATE 2 MG

Chronic constipation : Leads to many health problems. Get rid of it with......

A highly selective serotonin 5-HT4 receptor agonist which has been shown to stimulate gut motility in vitro and in vivo.

Effectively accelerates whole gut, gastric, small bowel and colonic transit in constipated patients.

Stimulates gastrointestinal enterokinetic activity in animals in both in-vitro and in-vivo studies

Free from any effect on anorectal motor function or impair rectal sensation in either healthy volunteers or patients with constipation.

Faster acting than other laxatives

Prucalopride has a rapid onset of enterokinetic activity and increases the number of complete spontaneous bowel movements. Adequate relief of constipation among patients with severe constipation occurs significantly more frequently in patients taking prucalopride compared with placebo.

[Georges Coremans : Core Evid. 2008 Jun; 3(1): 4554.]

Useful in drug-unbresponsive chronic constipation

Data from large randomized, controlled clinical trials indicate that it is effective in CC and offers a new therapeutic alternative for those whose condition fails to respond to conventional laxatives.

[Eamonn M. M. Quigley : Therap Adv Gastroenterol. 2012 Jan; 5(1): 2330.]

Indications :

- Chronic constipation

- Constipation due to spinal cord injury

- Constipation secondary to chronic daily opioid use

Dosage :

As per Guidelines of Doctor.

A 2 mg dose regimen appears optimal to start, with dose escalation when needed and dose reduction in the case of adverse events consistent with the prokinetic action that would preclude further treatment with 2 mg once daily.