About

It helps your body know whenit's time to sleep and wake up, Normally, mainjob in the body is to regulate night and day cycles or sleep-wake cycles.Darkness causes the body to produce more melatonin, which signals the body toprepare for sleep. Light decreases melatonin production and signals the body toprepare for being awake. Some people who have trouble sleeping have low levels.It is thought that adding might help them sleep.

Trouble falling asleep at a conventional bedtime (delayed sleep phasesyndrome). Taking by mouthappears to reduce the length of time needed to fall asleep in young adults andchildren who have trouble falling asleep.

v At bedtime seems to improve sleep in children andadults who are blind.

v Beta-blocker drugs, such as atenolol andpropranolol, are a class of drugs that seem to lower melatonin levels, thismight cause problems sleeping. Research shows that might reduce problemssleeping in patients taking beta-blocker drugs.

vDaily for 8 weeks seems to reduce pain and painkilleruse in women with endometriosis. It also reduces pain during menstruation,intercourse, and while going to the bathroom.

v  Short-term seems to shorten the amount of time it takes to fallasleep in people with insomnia, but only by about 7-12 minutes. Might alsoincrease the amount of time that a person with insomnia spends sleeping. Thereis also interest using melatonin for people with insomnia and other conditionsmight improve sleeping trouble related to conditions such as depression,schizophrenia, epilepsy, autism, developmental disabilities, and intellectualdisabilities.

v Most research shows that can improve certain symptoms of jet lagsuch as alertness and movement coordination, Also seems to slightly improveother jet lag symptoms such as daytime sleepiness and tiredness.

v  Used under the tongue seems to be aseffective at reducing anxiety before surgery as midazolam, a conventionalmedication. Taking by mouth also seems to reduce anxiety before surgery,although some conflicting evidence exists. Furthermore, some evidence suggeststhat taking before sevoflurane anesthesia reduces agitation after surgery.

v Taking high doses with chemotherapy or other cancer treatmentsmight reduce tumor size and improve survival rates in people with tumors.

v Research suggests that at bedtime for 4 weeks reduces pain by 44%and increases tolerance to pain by 39% in women with jaw pain.

v  Can improve low blood platelet countsassociated with cancer, cancer treatment, and other disorders.

v

v: 0.5 mg to 5 mg taken daily before bedtime forup to 6 years has been used in blind people, high dose of 10 mg an hour beforebedtime for up to 9 weeks. 2-12 mg taken at bedtime for up to 4 weeks.

v: 0.3 to 5 mg daily for up to 9 months.

v:2.5 mg daily for up to 4 weeks and single doses of 5 mg.

v: 10 mg daily for 8weeks.

v: 2-3 mg ofcontrolled-release for 4 weeks.

v:

o  o  v: 0.5-8 mg at bedtimeis commonly taken on the day of arrival at the destination, continuing for 2 to5 days. Low doses of 0.5-3 mg are often used to avoid the side effects of thehigher doses.

v: 3-10 mg taken 60-90 minutes before surgery.

v: 10-40 mg daily,along with radiotherapy, chemotherapy, or interleukin 2 (IL-2), typicallystarted 7 days before the start of chemotherapy and continued throughout fulltreatment course. 20 mg intravenously daily for 2 months, followed by 10 mg oforal melatonin daily.

v: 5 mg at bedtime for 4 weeks.

vForlow levels of platelets in the blood (thrombocytopenia) associated with cancerchemotherapy: 20-40 mg dailybeginning up to 7 days before chemotherapy and continuing throughoutchemotherapy cycles.